However, little effort has been made to study the potential effects of combined morphological and membrane alterations on signal transfer and synaptic integration in neurons that build up affected neural networks in AD. Amyloid-related dendritic atrophy and membrane alterations of susceptible brain neurons in AD, and in animal models of AD are widely recognized. One century after its first description, pathology of Alzheimer's disease (AD) is still poorly understood. Somogyi, Attila Katonai, Zoltán Alpár, Alán Wolf, Ervin A Novel Form of Compensation in the Tg2576 Amyloid Mouse Model of Alzheimer's Disease.
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